The 338 with heavies isn’t a bad idea at all. If your man enough to handle it & not be scoped constantly. I’m not a big dude so I shoot lesser caliber with heavy per caliber loads. But I do have a 264win launching 120/127g barns 3250/3300fps. Use it sitting on ground in brush piles on whitetail bucks 150-400 yards they’re dead right where I hit em. I do shoot a lot & sight to make spine shots. Also use a custom 284 win 70 with 150s at 3050fps. It uses less powder & puts deer down instantly if I do my part with minimal meat waste. That’s the goal for me, don’t destroy 1/2 a deer just to get it!